Course Title: Gut Microbiome: Role of Probiotics in Human Health
LEVEL 01 (UNDERGRADUATE STUDENTS)
Course Duration: 8 weeks
Meeting Times: 2 hours/week
Meeting Location: Online
CONTACT INFORMATION:
Instructor:
Dr. Asma Bashir
Ph.D. (Biosciences), MS (Biosciences) & M.Sc. (Microbiology)
Lecturer, Faculty of Life Sciences
SZABIST University
Email: [email protected]
Phone: 0092-3331350269
Contact Hours: By appointment
Invited Speakers:
Prof. Dr. Kashif Ali
Ph.D. Systems Biology, Leiden University, Netherlands
Dean, Faculty of Life Sciences, SZABIST University
Email: [email protected]
Ms. Neha Farid
Masters in Biosciences, SZABIST University
Lecturer, Faculty of Life Sciences
SZABIST University
Email: [email protected]
COURSE OVERVIEW:
Over 10 trillion microbes reside in our guts, which is an interesting fact. In actuality, these bacteria are present throughout our bodies, both inside and outside. These living bacteria engage in diverse interactions and influences on our body’s varied processes. Therefore, it is crucial to educate yourself about these bacteria and how they affect our health. Our health and wellbeing are directly impacted by their close interaction.
You will learn about the fascinating human microbiome and how it affects our nutrition and health in this online course. The main goal of the course is to give participants a fundamental grasp of the microbiome and its uses in the gut.
COURSE DESCRIPTION:
This course provides an overview on the role of microbiome in human health and disease. It focuses on conceptual framework and technologies for understanding how microbiome, particularly gut microbiome impact human health and well-being, students will be able to go on a fascinating journey into the human body – down to the gut – where the ecology and roles of the human microbiome will be narrated.
COURSE LEARNING GOALS:
By the end of the course, students will be able to:
- Illustrate ecological principles of the human gut microbiome, and the importance of conservation of the global microbiomes of peoples from different human populations
- Examine how gut microbiome may impact human health
- Summarize the tools and strategies for studying and identifying the gut microbiome
- Assess the potential of the microbiota (probiotics) and diet (prebiotics) to achieve and maintain health
ASSIGNMENTS/RESPONSIBILITIES, GRADING & ASSESSMENT:
Examinations 2 x 20 points = 40 pts
Essays 2 x 30 points = 60 pts
Total = 100 pts
COURSE SCHEDULE:
| Week 1 | Introduction: Human super organism; Microbiome and human adaptation/evolution |
| Week 2 | Ecological principles of microbiomes; Are probiotics bacteria? Probiotics development and functions in early life and physiological changes during the life-span |
| Week 3 | Food processing and gut microbiome |
| Week 4 | Influence of different bioactive food components on gut microbiome |
| Week 5 | Human Microbiome and the gut diseases |
| Week 6 | Effect of antibiotics on gut organisms |
| Week 7 | Laboratory Experiment: Isolation and Identification of gut microbes (Gram Staining and Biochemical Tests) |
| Week 8 | Laboratory Experiment: Molecular Identification (DNA Extraction, DNA Amplification by PCR) of the gut microbes |
| Week 9 | Laboratory Experiment: Sequencing of the gut microbes (Sanger Method) |
| Week 10 | Laboratory Experiment: Making Sense out of gut microbial data; development of tools for analyzing large, complex biological data sets |
Course Title: Gut Microbiome: Role of Probiotics in Human Health
LEVEL 02 (MASTER STUDENTS)
Course Duration: 8 weeks
Meeting Times: 2 hours/week
Meeting Location: Online
CONTACT INFORMATION:
Instructor:
Dr. Asma Bashir
Ph.D. (Biosciences), MS (Biosciences) & M.Sc. (Microbiology)
Lecturer, Faculty of Life Sciences
SZABIST University
Email: [email protected]
Phone: 0092-3331350269
Contact Hours: By appointment
Invited Speakers:
Prof. Dr. Kashif Ali
Ph.D. Systems Biology, Leiden University, Netherlands
Dean, Faculty of Life Sciences, SZABIST University
Email: [email protected]
Ms. Neha Farid
Masters in Biosciences, SZABIST University
Lecturer, Faculty of Life Sciences
SZABIST University
Email: [email protected]
COURSE OVERVIEW:
Over 10 trillion microbes reside in our guts, which is an interesting fact. In actuality, these bacteria are present throughout our bodies, both inside and outside. These living bacteria engage in diverse interactions and influences on our body’s varied processes. Therefore, it is crucial to educate yourself about these bacteria and how they affect our health. Our health and wellbeing are directly impacted by their close interaction.
You will learn about the fascinating human microbiome and how it affects our nutrition and health in this online course. The main goal of the course is to give participants a fundamental grasp of the microbiome and its uses in the gut.
COURSE DESCRIPTION:
This course provides an overview on the role of microbiome in human health and disease. It focuses on conceptual framework and technologies for understanding how microbiome, particularly gut microbiome impact human health and well-being, students will be able to go on a fascinating journey into the human body – down to the gut – where the ecology and roles of the human microbiome will be narrated.
COURSE LEARNING GOALS:
By the end of the course, students will be able to:
- Illustrate nutritional requirements of the human gut microbiome, and the importance of nutrition of the global microbiomes of people from different human populations
- Examine how gut microbiome may impact pregnancy and birth
- Summarize the tools and strategies for innovative approaches to modify the gut microbiota
- Assess the potential of the gut microbiota in the metabolic pathways to achieve and maintain health
ASSIGNMENTS/RESPONSIBILITIES, GRADING & ASSESSMENT:
Examinations 2 x 20 points = 40 pts
Essays 2 x 30 points = 60 pts
Total = 100 pts
COURSE SCHEDULE:
| Week 1 | Nutrition and gut microbiome; Gut Microbe-Host Interactions: Beyond nutrition |
| Week 2 | Infections, allergies and inflammatory bowel diseases; The gut microbiome and host immunity: animal models |
| Week 3 | Nutritional modulation of the gut microbiome for metabolic health: human obesity |
| Week 4 | Nutritional modulation of the gut microbiome for healthy longevity and metabolic health: animal models |
| Week 5 | Gut Microbiota perturbations: medical practices |
| Week 6 | Gut Microbiota transmission: pregnancy and birth |
| Week 7 | Pharmaceutical modulation of the gut microbiome for metabolic health |
| Week 8 | Innovative approaches to modify the gut microbiota on industrial scale; Solutions in gut microbiome engineering; Fecal Microbial Transplantation |
| Week 9 | Food and Drug Administration (FDA); Food and gut microbiota in the FDA regulatory framework
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Week 10 |
Establishing reference reagents for the analysis of the gut microbiome on industrial scale; Diet Approach to Modulate Gut Microbiota |
