Green Biotec UG Bremen Germany
Introduction to Bioinformatics
| Introduction to Bioinformatics | |
|---|---|
| Course Description | Bioinformatics combines computer programming, big data, and biology to help scientists understand and identify patterns in biological data. This course provides comprehensive training in bioinformatics tools, databases, and techniques, focusing on their application in genomics, proteomics, and drug discovery. Students will learn to analyze and interpret biological data to meet modern-day research and industrial needs. |
| Recommended Books | 1. Bioinformatics: Sequence and Genome Analysis by David W. Mount 2. Practical Bioinformatics by Agostino Riva |
| Course Learning Outcomes | After completing this course, a student will be able to: 1. Understand the fundamental concepts and applications of bioinformatics. 2. Utilize biological databases for gene and protein analysis. 3. Perform in silico sequence analysis, gene amplification, and expression analysis. 4. Gain hands-on experience with bioinformatics tools and software. |
| Assessment System | Quizzes: 10-15% Assignments: 5-10% Midterms: 30-40% End Semester Exam: 40-50% |
| Lecture Plan | ||
|---|---|---|
| S.No. | Description | Quizzes/Assignment |
| 1 | Introduction to Bioinformatics: Scope and Applications | Quiz 1 |
| 2 | Biological Databases: Literature Search and Data Retrieval | |
| 3 | Gene and Protein Sequence Databases: NCBI, EMBL, PDB | Assignment 1 |
| 4 | In Silico Sequence Analysis: Genome Browsers and Gene Finding | |
| 5 | Sequence Alignment: Pairwise and Multiple Alignment | |
| 6 | Dynamic Programming for Sequence Alignment | Quiz 2 |
| 7 | Gene Amplification: Primer Designing and Restriction Analysis | |
| 8 | Expression Analysis: Microarrays and Alternative Promoters | |
| 9 | Protein Sequence Analysis: Functional Annotations | Assignment 2 |
| 10 | Function Prediction: Structure-Function Relationship | |
| 11 | Hands-on Practice: ClustalW, Primer3, OligoCalc | Quiz 3 |
| 12 | Tools for Protein and DNA Analysis: BLAST, EMBL, Uniprot | |
| 13 | Case Studies: Bioinformatics Applications in Drug Discovery | |
| 14 | Recent Trends: Advances in Bioinformatics Tools | Assignment 3 |
| 15 | Future Directions: Bioinformatics in Personalized Medicine | |
